Patient Access / Caregiver / Physician / or Counselor 

The Problem

Opiate overdose deaths are increasing in the US and worldwide particularly with the increased availability of fentanyl and other synthetic opioids. A 30 percent  annual increase to 100,000 opioid overdose deaths occurred in the US from May 2020 to April 2021.

1 million US patients/yr receive outpatient treatment for opioid use disorder.  Our site provides telemedical solutions for the diagnosis, prevention, and treatment of opioid use disorder.

Neuro-metabolic theory for Opioid Use Disorder

Prevention of Opioid Use Disorder

Prevention can be accomplished by risk analysis looking at  :

  1. presence of one DSM-5 criteria for opioid use disorder. 
  2. psychogenetic risk factors
  3. intestinal microbiome biomarkers – lower fecal bacteria biodiversity, specific microbial species and their metabolites
  4. metabolic  biomarkers 
  5. psycho-social-economic risks factors 
  6. opioid availability and/or prevalence of OUD .
  7. prior history of magic mushroom/Psilocybin  use

Predictive models have been developed to determine the propensity for opioid use disorder as well as its diagnosis.  The predicted propensity value can be used to target high risk  groups with evidence based interventions as well as personalize individual intervention programs .

Diagnosis and treatment of opioid use disorder

Opioid addiction therapy includes :

Literature and Related Sites