1. Jelly roll capsids evolved from single to double beta barrels. Gamma Sphaerolipoviruses in Archaea/Eubacteria and ( Microviridae – ssDNA in eubacteria/archaea ) have single jelly roll while Tectiviridae have double jelly roles.
2. PolB and Cas1 casposons are related to Polintoviruses and may be responsible for the evolution of the CRISPR CAS adaptive immunity in Archaea and Bacteria
3. PolA and Cas4 transposons may be related to rudiviridae and ssDNA Innoviruses. Also related to poxviruses, chlorella virus, and african swine fever virus.
4. Cas9 containing transposons may give rise to another class of viruses.
5. Insertion sequences may evolve into plasmids and then acquiring envelopes or capsids to become viruses.
6. Pre LUCA cells may have evolved into HK97 and jelly roll capsid based viruses containing PolA, PolB, and PolC dna polymerases (ie. the caudiviralis and microviridae-tectoviridae ) via reductions in their genomes.
Protein primed DNA polymerase B family – ampullaviridae, fuselloviridae, & pleolipoviridae are archaeal viruses while casposons are dna transposons.
Globuloviridae – PSV1, TTSV1 – linear dsDNA
PortoGlobuloviridae – SPV1 circular dsDNA
Metallosphaera Turreted Icosahedral Viridae – MTIV1, MTIV2 – linear dsDNA
Methanosarcina Spherical Virus – MetSV lipid containing, linear dsDNA
Clavaviridae -APBV1 major viral protein with blast similarity to myovirus tail proteins
Caudiviralis – Archaeal tailed viruses with (HK-97 capsid protein fold)
Myo – PhiH-like = Halobacterium phage ϕH, Halobacterium phage Hs1, (HF2 , HF1, HRTV-5, and HRTV-8) (HRTV-7 and HSTV-2), HGTV-1
Sipho – (HCTV-1, HCTV-5, and HVTV-1) , (HCTV-2 and HHTV-2), HHTV-1 , HRTV-4 and BJ1, ϕCh1, Nvie-Pro1 provirus in thaumarchaea : possibly myo
Podo – HSTV-1
TECTIVIRIDAE -with beta barrel/jelly roll folds
Sphaerolipoviruses = Halosphaeroviruses – PH1, SH1, HHIV2, SNJ1 -jelly roll capsid
Alpha HHIV-2, PH1, SH1
Beta SNJ1
Gamma (Thermus bacterial IN93, P23-65H, P23-72 P23-77) and provirus ArcVen-P3 from Archaeoglobus veneficusSNP6 and provirus in choroflexi -dehallococcoides
Turriviridae -jelly roll capsid
alpha – STIV1, STIV2
I – HHPV1, HRPV-6, HRPV-2, HRPV-1ssDNA
II – HRPV-3, HGPV-1
III – HIS2
Guttaviridae
alpha – ? SNDV
beta – APOV1
CAS4 like Major Coat Protein Viruses
Ligamenviralis
Rudiviridae – SIRV1-2, SRV, ARV1, SMRV1
Lipothrixviridae -AFV1-9, SIFV,TTV1
Ampullaviridae -ABV
alpha – ATV
beta – STSV1, STSV2
Fuselloviridae/Monocaudaviruses – SMF1, SMV1
alpha – SSV1-5
beta – ASV1, SSV-6 –
gamma – APSV1, ?SSV-7
delta – PAV1, TPV1, A3-VLP
epsilon – HIS1
HAV2 (tadpole shaped/?fuselloviridae ) in hyperthermophiles
CAS4 and PolA containing viruses in hyperthermophiles
HAV1 ?rudiviridae
SpiraVirus -ss circular DNA virus -ACV
