Viral structural or Non structural proteins (NSP’s) .

Viral RNA polymerase (nsp12) replication/transcription Enzyme inhibitors or g/sg RNA terminators/mutators: iv Remdesivir = delayed terminator from Gilead ( FDA approved ) . Not recommended by the World Health Organization.

Viral Spike Protein Receptor Binding Blockade /Neutralization : Eli Lilly’s monoclonal antibody-LY-CoV555 and Regeneron -Roche 2 monoclonal antibody combination have FDA Emergency Use Authorization for use in early infection (prior to development of endogenous antibodies) in high risk patients.

ProTac molecular medicines contain VHL like sequence peptide tags chemically linked to a molecular agent with viral or host protein binding capabilities. ProTACs target the protein (viral nsp/structural proteins/ or complicit host proteins ) to E3 ubiquitin ligase which ultimately result in proteolysis by the Cytosolic Proteosome.
Experimental Treatments

Salicyn-30, Niclosamide (?glucose transporter inhibitor, STAT 3 Inhibitor, Beclin-1 stabilizing, hydrogen ionophore/lysomotropic )
Fluvoxamine – antiviral effects via its lysosomotropic properties,24 modulation of the effect of IRE1 effects on autophagy,²⁵ and SSRI inhibition of platelet activation- or activation of the sigma 1 Receptor., and/or anti-inflammatory properties, inhibition of virus release via the lysosomal exocytosis pathway by blocking acid sphingomyelinase .

Zinc + zinc ionophores: Zinc with drug X, quercetin from honey, ECGC from green teas, zinc + chloroquine.