Molecular and Cellular Simulation of AD Pathogenesis

Genetic profile , Lifestyle, and Age based Disease Stratification

Dementia/Alzheimer’s  Disease Clinical Guidelines

San Diego County Alzheimer’s Project

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Imaging or Other Reasons

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Healthy Body, Healthy Mind & Tools for Navigating Dementia

Treatment : Mechanism of Action
Omega 3 fatty acids , Superoxide Anion Detoxifiers/Production Inhibitors – Reducing Neuroinflammation
Stimulating Glymphatic Drainage of the Brain during Deep Sleep through prevention of AQP4 delocalization in periarterial Astrocyte Endfeets.
Lithium Orotate – Glycogen Phosphate Kinase beta inhibitor
Polyphenols –Anti Tau and Amyloid beta protein aggregationUrolithin A – control naive/senescent CD8 ratio
Probiotic Nutritional Fibers with enteric microbiome metabolization: Ferulic Acid, Butyrate, and Short Chained Fatty Acids
Womens supplements
Vitamin D3, K2, and Mg – General Nutrition
Vitamin B12 – Brain Nutrients
Anti amyloid protein antibody injections
BACE1 aspartate protease inhibitors,
Plasminogen protein infusions
Acetylcholine Esterase Inhibitors
Incretins – GLP-1 – GIP agonists
Varicella Zoster Vaccine – Vaccinations against Neurotropic Viruses or Bacteria
SGLT2 inhibitors
C1q complement cascade -Inhibitors or Enhancers

Experimental Treatments

Observational Study of Apo E4 heterozygous subjects with high Polyomic Risk Scores ( Genetics ,Lifestyle, Biome, and Immunome ).