Types of AD
| Clinical Scenario | Core ICD-10 Codes | Add-on Codes/Notes |
|---|---|---|
| Early-onset (DIAD/EOAD) | G30.0 | F02.8x, genetic variant in note |
| Late-onset (LOAD) | G30.1 | F02.8x, note ApoE4 & PRS |
| Down’s + Alzheimer’s | Q90.x + G30.x | F02.8x for dementia |
| Mixed: AD + LBD | G30.x + G31.83 | F02.8x or F03.x |
| AD + Vascular Dementia | G30.x + F01.x | F02.8x |
| AD + Prion Disease | G30.x + A81.0 | F02.8x |
| AD with Herpes Simplex | G30.x + B00 | F02.8x if dementia |
| AD with Substance Use | G30.x + F10–F19 | F02.8x |
| Sporadic/Recessive AD | G30.8 | F02.8x |
| Unspecified AD | G30.9 | F03.x |
Definitions
- AD = Alzheimer’s Disease
- DIAD = Dominantly inherited Alzheimer’s Disease (APP, Presenilin 1, or Presenilin 2 pathological variants)
- Trisomy 21 = Down’s Syndrome – resulting in 3 APP genes.
- ApoE4 homozygotes – EOAD Early Onset Alzheimer’s Disease
Genetic profile , Lifestyle, and Biological Age based Disease Staging
Dementia/Alzheimer’s Disease Clinical Guidelines
San Diego County Alzheimer’s Project
Request an Online Visit with Dr. Carr for
- Mini-Cog, and the MiniMental Status Exam
- ApoE genotyping and Polygenic Risk Factor Assessment
- Biomarker testing : Blood pTau217, Amyloid Beta 40/42 Ratio or under development
- Longitudinal Inflammation Monitoring
- General physical 100 Biomarker Blood Panel
- Point of Care Testing Solutions
Imaging or Other Reasons
- Retinal Scanning for AI Assisted Early Diagnosis
- beta amyloid PET Brain Scan
- Tau Pet Brain Scans
- TSPO-Neuroinflammation Biomarker PET Scans
Request a Personalized Treatment Plan
Healthy Body, Healthy Mind & Tools for Navigating Dementia
| Treatment : Mechanism of Action |
| Omega 3 fatty acids , Superoxide Anion Detoxifiers/Production Inhibitors – Reducing Neuroinflammation |
| Stimulating Glymphatic Drainage of the Brain during Deep Sleep through prevention of AQP4 delocalization in periarterial Astrocyte Endfeets. |
| Lithium Orotate – Glycogen Phosphate Kinase beta inhibitor |
| Polyphenols –Anti Tau and Amyloid beta protein aggregation |
| Probiotic Nutritional Fibers with enteric microbiome metabolization: Ferulic Acid, Butyrate, and Short Chained Fatty Acids |
| Womens supplements |
| Vitamin D3, K2, and Mg – General Nutrition |
| Vitamin B12 – Brain Nutrients |
| Anti amyloid protein antibody injections |
| BACE1 aspartate protease inhibitors, |
| Plasminogen protein infusions |
| Acetylcholine Esterase Inhibitors |
| Incretins – GLP-1 – GIP agonists |
| Varicella Zoster Vaccine – Vaccinations against Neurotropic Viruses or Bacteria |
| SGLT2 inhibitors |
| C1q complement cascade -Inhibitors or Enhancers |