Appetite Suppressants :

Decrease  meal size and frequency by inducing satiety, reducing hunger, and/or reducing gastric emptying.

Drugs prescribed:

GLP-1 agonists :  Trulicity,  Ozempic  / 2.4 mg semaglutide sc injection,  oral Rybelsus, or Tirzepatide 5mg – 15mg intradermal autoinjector (GIP and GLP-1 agonist)

Antagonism of ghrelin’s (hunger hormone) activation of the NPY/Agouti Related Peptide Orexigenic Response

Sympathomimetic Agents : Norepinephrine, Epinephrine, Methamphetamine, Phentermine, Didrex, Tenuate , Bontril , or ephedrine

Melanin Concentrating Hormone Reduction or MCHR1 AntagonismLeptin from Subcutaneous Adipocytes

MC4 Receptor Agonists :alpha-MSH Orexin inhibitors Hoodia Cactus Ingredient

P57 Cannabanoid CB1 Receptor Antagonists

Dietary oleate or tiolein and oleylethanolamide via CCK and capsaicin sensitive peripheral sensory neurons

Neurotransmitter Reuptake Inhibitor (ie Serotonin) : Meridia 

Apo A-IV from Chylomicrons via the hypothalamus

 Peptide YY 

Ciliary Neurotrophic Factor 

Melanin Concentrating Hormone Reduction or MCHR1 Antagonism 

Leptin from Subcutaneous Adipocytes