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- Proteostasis modulators connected to the NPRx Inflammasome
- ER Membrane Associated Mitochondria (MAM) Sites Modulators,
- PPAR gamma or PPAR alpha modulators – activating Mitochondrial Use of Long chain fatty acids, SCFA, or Ketones.
- Prevent the Generation of PUFA hydroperoxides and other Reactive Oxygen Species
- Stress Granule Modulators,
- T cell – Microglia communication modulators, and
- Astrocyte – Microglia communication modulators.
- Microglia – Neuron communication/synaptic interaction modulators
- Endolysosomal System modulators – including exosome production and release.