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- Proteostasis modulators connected to the NPRx  Inflammasome
 
- ER Membrane Associated Mitochondria (MAM) Sites Modulators, 
 
- PPAR gamma or PPAR alpha modulators – activating Mitochondrial Use of Long chain fatty acids, SCFA, or Ketones.
 
- Prevent the Generation of  PUFA hydroperoxides and other Reactive Oxygen Species
 
- Stress Granule Modulators, 
 
- T cell – Microglia communication modulators, and 
 
- Astrocyte – Microglia communication modulators.
 
- Microglia – Neuron communication/synaptic interaction modulators
 
- Endolysosomal System modulators  – including exosome production and release.