Framework : Prokaryotic Cell Evolution

Bacterial Vesicles / Organelles- Potential PreCellular Life Forms


Cell Biology of Prokaryotic Organelles

Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly


Cell Biology of Prokaryotic Organelles

A spatial model of the chromatophore vesicles of Rhodobacter sphaeroides and the position of the Cytochrome bc1 complex

Proteomic characterization of the Rhodobacter sphaeroides 2.4.1 photosynthetic membrane: identification of new proteins


Cell Biology of Prokaryotic Organelles


Cell Biology of Prokaryotic Organelles

Polyphosphate granules/Volutin granules/acidocalcisomes

Elements involved in the biogenesis of these vesicles include: vacuolar proton pyrophasphatase AP-3, and rab 11, polyP kinases (ppks), polyP-dependent glucokinases (ppgks), phosphate transporters (pits), ppx gene for exopolyphosphatase, phaABC genes polyP kinases (ppks), two polyP-dependent glucokinases (ppgks)for PHA synthesis , actP gene for acetate/H+ symporter.

Unusual polyphosphate inclusions observed in a marine Beggiatoa strain

Adaptor Protein-3 (AP-3) Complex Mediates the Biogenesis of Acidocalcisomes and Is Essential for Growth and Virulence of Trypanosoma brucei

Evolution of vacuolar proton pyrophosphatase domains and volutin granules: clues into the early evolutionary origin of the acidocalcisome

Deciphering the Genome of Polyphosphate Accumulating Actinobacterium Microlunatus phosphovorus

Volutin granules of Eimeria parasites are acidic compartments and have physiological and structural characteristics similar to acidocalcisomes


Mg, Ca, Strontium, and Barium Carbonate Nanoballs in Cyanobacteria

hypothesized functions:

1. Protection from Gamma , Xrays, and UV radiation

2. Photosynthesis using Gamma Rays and Xrays

3. Motility Organelle : ie. Balasts for positioning in the hydrological goldilox zone

4. Chemolithotrophy involving free radical oxygen.

5. Organization of the formative electron transport chain

6. Storage of Carbon, Oxygen, and Hydrogen for macromolecular biosynthesis.

7. Chemosensory organ


Nitrate Vacuoles

Vacuolated Beggiatoa-like filaments from different hypersaline environments form a novel genus.

Secretin Structures

Secretins: dynamic channels for protein transport across membranes


Bicarbonate producing Organelles


ATP Sequestration by a Synthetic ATP-Binding Protein Leads to Novel Phenotypic Changes in Escherichia coli

Secreted membrane vesicles

Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles.

Membrane vesicle release in bacteria, eukaryotes, and archaea: a conserved yet underappreciated aspect of microbial life

Evolution of diverse cell division and vesicle formation systems in Archaea.

Crenarchaeal CdvA Forms Double-Helical Filaments Containing DNA and Interacts with ESCRT-III-Like CdvB

©2012 Foster P. Carr MD all rights reserved